HERG (LQT2)

Mutations - - Polymorphisms - - Locus Table


 

Chromosome

Band

Marker

Amplimer

PCR Product*

LOD Score#

7

q35-q36

D7S483

 AFM074xg5 166-188  19.41(1)

7

q35-q36

D7S505

 AFM199zd4  262-278  

* fragment size in base pairs

# Lod score for linkage to disease locus; (1) Combined LOD score in 9 families.

Linkage: Linkage of LQTS phenotype with the chromosome 7 (7q35-36) was first demonstrated by Jiang et al. in 1994.

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