KCNE1

KCNE1 mutations - KCNE1 synopsis


 

Chromosome

Locus

Marker

21

21q22.1-q22.2

D21S65

21

21q22.1-q22.2

D21S219

 Search UniSTS for KCNE1

Linkage: Genetic linkage of congenital long-QT syndrome of subtype 5 to the KCNE1 locus has not been shown yet due to the lack of large families.

The causative role of the KCNE1 gene in LQT5 is suggested by individual mutations in patients with LQT syndrome that each have been shown to result in a reduced I(Ks) current during in-vitro analysis.

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